First of all, good luck to all of us and may God bless you! We are in a situation which seems to be unpredictable and where results are always given in percentages and maybes. I have had two, four month shots of Lupron and the third is coming at the end of June. My PSA was never that high, 3.0 when started on hormone treatments and after 35 aimed radiation treatments which was supposed to reduce my PSA. I now have metastic leisons to the scapular, which seems to be getting worse. Not sure if it is bone invasion or muscular since I vigorously excercise every day. The radiation took my PSA from 1.0 to 1.4, poor results since all the doctors concluded it would be a local recurrence, which apparently it was not. The Lupron brought it from 3.0 to 1.7 and the next PSA is coming soon. If one has to hate something, this disease would be it.