Hi i was dia sept 06 grade 4 gbm right t lobe,i had the tumour back in 2001 but it wasnt until my op in sept 06 they found the cancer,anyway they took out the tumour ,radiation 6wks temodal 6 wks now then temodal 18mths,last cycle this week as the doc said yesterday long term use could cause leukemia in some havnt had so much as a headache throughout anything,my q how does it all start ?regards and good wishes john.