The problems I am aware of involve Paxil or other SSRI's and tamoxifen. The problem appears to be that Paxil and SSRI's can prevent the liver from converting tamoxifen into its active form. If you were on tamoxifen then switching your antidepressant to Effexor appears to help and avoids the interaction. I am not aware of any problem with Aromosin and Paxil.