My husband was dx'd in 2/2007 with GBM. Tumor was a butterfly glioma with most of the left front lobe tumor removed. The right side was untouched because that would have been too aggressive. He completed radiation and 11 cycles of Temodar, which further reduced both parts of the tumor. Our recent MRI showed a finger growth in the left hemisphere, so we are discontinuing Temedor and starting Avastin/CPT11 soon. How hard is the Avastin/CPT11 on the body? What are the side effects I can expect? Thanks for the info.