I hope this isn't an insensitive or dumb question but I'd like to know how others have approached this. If and when there comes a point that the treatment is taking such a toll on quality of life that it's not worth it, how do you recognize this point?? Do you let the doctors tell you first that they've done all they can? Do you just "instinctly" know? I want myself and my husband to fight this cursed disease with all we have but at the same time, doesn't this have to be weighed against quality of time and living life on one's own terms? I really don't have any answers right now. In fact, I pray we never get to this crossroad.