My mom had 400mg Temodar in Feb. that knocked her for a loop! She could not walk a straight line and was grabbing furniture/counters for support! Her med.onc's NP said that its not uncommon and actually my mom's case was mild compared to some that she has seen on Temodar. It did pass but she was literally laid up for 8-10 days post Temodar! Her counts bottomed-out to the low 30's - any lower they were going to transfuse her. The next Temodar round they cut back the dose to 280mg and she did MUCH better! Make sure to talk to your med.onc - he acknowledge that my mom's symptoms were neurotoxicity to the Temodar. - Nikki
Mom 10/07 resection Lt. parietal plum-size GBM; rad/Temodar; 2 rounds Temodar; post Gamma Knife now - battling to control seizures currently