I get hot flashes with the Lupron, but I personally feel its a plus. Sweating from the hot flashes burns up calories which in turns helps keep your weight lower. My weight has dropped 8 lbs since starting lupron. And you know lupron is not really benedicial for your heart- so I look at this way it keeps me more trim and not get overwieght. So good things can occur with the uncomfortable at the same time. Tip- drink or use fat free soy milk with your cereal, avoid meat and dairy products and avoid eggs.Good luck