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Clomipramine + Temodar??

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Sister-mar
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Subject: Clomipramine + Temodar??
Date: 05/14/2008

After reading posting of 4/28/08 concerning the usage of clomipramine I decided, why not?  Our neuro-onc. had never heard of this usage but said it couldn't hurt.  I wondered if a low-dose daily Tem. should be used in conjunction with this.

 Brother dx. 9/11/07, inoperable GBM, almost tennis ball size.  I posted the "Stable MRI but patient decling"  message 5/4/08.

 We've stopped the 5/23 Temodar after 5 rounds post rad/chemo combo.  Will probably try the Avastin-CPT 11 and see if he can tolerate it.  Worried about the 2-3% chance of stroke or hemmorage during treatment, but at this rate he'll just get worse and slowly die.

Anyone heard of patients having stroke during Avastin treatment?

  

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