My husband had Cisplatin, they gave him 3 Emend tablets, one before his treatment, and one the next two days. He wasn't sick after any of his treatments, just tired.....(we paid $120.00 for the Emends)......one suggestion the Dr. didn't tell us until later, if you have a gold or silver tooth, pack it with a wod of gum, so you don't get a double dose of radiation, or chemo. My husband had a terrible mouth ulcer on his tongue because of it. That was probably the worst thing he had to deal with for a few weeks...