Hello....I have posted messages here before and gotten several helpful and caring responses so I thought maybe I would be able to get some advice. My son was diognosed last June with Glioblastoma, the original tumor was in the parietal area. After radiation and Temodar, he had recurrence in the same area, then went on Avastin & Ironitecan. While on the avastin & Ironitecan, he developed Hydrocepahalus. While recovering from surgery a new tumor in the temporal lobe and we just found out the cancer cells have spread to his spinal fluid and the lining of his brain. The Dr. said MRI a month ago showed only 1/2 the meninges enhanced, now the entire lining enhances. He had a spinal tap and it was positive for cancer cells. Obviously I am very worried. I know it is bad but I try to keep hope. He has had such a hard year, it almost seems like its one thing after another. In the past month alone we have been in Birmingham (UAB) 20 days, we live 3 hours away. ANYWAY... I was wondering if anyone has had a loved one that has had this happen. We have been given a grim prognosis but he will go thru a clinincal trial starting next week. It is Cytoxin, synthetic Scorpion Venom. Any advice will be so appreciated....Thanks so much!