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Is This Even Possible?

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Subject: Is this even possible?
Date: 06/16/2008

Please advise if you have had a similar experience.  My father was recently diagnosed w/ cancer of unknown primary, w/ mets in the liver and mets in the lungs. 

 He had a recent colonoscopy/endoscopy that was clean, but had one in the summer of 2007 that led to a follow-up colonoscopy in November 2007, which resulted in the removal of large polyps that were supposedly benign.  This immediately preceded the onset of his symptoms.

 The doctors who had been seeing him wanted to start him on chemo w/ drugs that attack colon cancer, but we are having a difficult time understanding this recommendation.  Is it possible that he could have colon cancer with a clean colonoscopy?  (Perhaps, even that the polyps that were removed before could have been his primary cancer?)  We are perplexed and trying to figure this all out, and would be grateful to know whether anyone has ever traced Stage 4 cancer to "benign" polyps that later turned out to be cancer.

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