A family member was diagnosed with mucosal melanoma (vaginal) in Dec 05, at which time the mass was removed. She then had an additional surgery, in Jan 06, to remove more tissue around the original tumor site. She began taking Interferon (5 days/week for 4 weeks - followed with 3 days/week for 8 months). In October, 2006 the disease had metastasized to the liver. She was put on Temador from Jan 07 to Apr 07. The next scan in Apr 07 showed the disease had spread to one lung and the original tumors had increased. She began taking Taxol and Avastin in May 07 and the tumors began decreasing. She was on Taxol and Avastin from May 07 to Apr 08. The Apr 08 scan showed the Taxol and Avastin was not decreasing the tumors anymore. She was then put on Carboplatin and had 2 treatments. The Carboplatin caused a severe decline in her platelets, resulting in 2-3 platelet transfusions. Her WBC and hemoglobin suffered as well. She missed treatments due to the side effects. Her last scan was the end of June 08 and her tumors had increased. She has now been prescribed Gleevec. She will take Gleevec for 2 months and then have another scan. Does anyone have any information that you could share on mucosal melanoma??? If so, what treatments were given and their success??? Since this is such a rare form of cancer, very little information exists. Any information (AND PRAYERS) would be greatly appreciated.