I am stage 4 NSCLC and have been on Avastin and Tarceva for two years and then just Tarceva for the last 7 mos. (I also had cyberknife treatment). I am holding stable with cleared bone mets and only a small area that might only be scar tissue. Tarceva saved my life. In August, I will have survived 3 years since diagnosis. I no longer have the digestive problems or nausea only some rash and toenail infections.