Hi Mark - If you go to Cathy's Cafe website, you'll be amazed at the number of long term survivors of Stage IV. Many are well over 5 years and still NED. I lost my Dad to the first round of chemo for Stage IV at Hopkins, but, I am convinced after following the survivors on Cathy's Cafe that it does NOT have to a death sentence! There are many on there! Good luck to you Mark - My prayers are with you! karen