My wife is stage 3 lung cancer around her heart, we have been on tarceva for almost 4 months now, she started having a rash almost immeadiatly when taking the meds, heres how we coped with it, we started with the least invasive, which is over the counter benadril 25 mg tabs, and it worked no more rash she takes them about 30 min prior to taking her tarceva and doesn't get any rash, a simple benidril how cool, hope this helps others with Tarceva.