My name is Joe and im 36 years old.In April of 01 i was having issues getting sick and was diagnosed with a "reflux" disorder. I lived with what all the doctors told was just that reflux. Well in May06 it got to the point i was bed ridden. I went to see the doctors again and was told again it was exactly that. a reflux disorder. i went to a gastroentologist for a 2nd opinion. After an endoscopy/colonoscopy i was told i had plum sized tumor in my colon just past my appendix. I was 80% blocked and everything going through my system was bottle-necked and being pushed back up. it was colon cancer. four days later i had a right hemi-coloctomy removing the tumor , my appendix and about4-6 inches of both my colon and small intestine. I went through a full 15 treatments of lukovorin, 5FU and Oxcilaplatin. My oncologist before treatment ever started informed me of the possible side effects of the drugs including the PN. After even the first round of chemo i had the the PN effects. it lasted for around 4-6 days and then subsided leaving me with about 3-5 days of being PN symptom free before the next round of chemo. This cycle repeated itself through the next 6-7 treatments. Around the 8th treatment. the PN didnt go away. And gradually the effects got worse as chemo sessions progressed. It wasnt until i had 2 treaments to go before the dosage of the oxcilaplatin was reduced. and then only minimally. I finishd chemo the 2nd week of Dec 06. so it hasnt been that long. and the PN has only gotten worse. The effects plateaued last week. But its agonizing. My feet are constantly numb and tingly. they feel like they are asleep all the time. If the sheets or blankets move over my feet at night i wake up and have a hard time going back to sleep. this happens 2-3 times a night. And my hands, well i have a hard time writing now, tying shoes for my sons, etc. I repair fine electronics. I work with my hands. and now i no longer have a good sense of touch. And im not real sure how this is going to work out. I got a referral to a neurologist and saw him actually just today. He told me that the fact the sensations have plateaued bodes well plus my age which is relatively young for all that has happened. anyways, he told me that at this point in time there is no real treatment for what is going on and only time will tell exactly how this is going to pan out. But he did prescribe me Symbalta. I believe its actually an antidepressant. He stated that the drug has had some good response to actually helping with the numbness and tingling sensations associated with PN. Anyways, I hope things improve for all you.