I have been on 150 mg of Tarceva daily for almost 11 months now. Have had all the typical side effects including bleeding sores inside my nose and sores on my head. About a month ago the head sores got so bad I had thick scabs all over my scalp and it burned, itched and I couldn't sleep. My oncologist reduced my dosage to 100 mg and gave me Bactran cream to use. The sores cleared up in a little over a week and I put myself back on the 150 mg dosage because I'm scared the 100 mg is not going to keep the tumors away. I have been back on the 150 mg dosage for about 2 weeks and all the side effects have returned and I'm feeling some spots on my scalp again, nothing like before though. Has anyone else been on less than 150 mg and how did it work with the tumors? My tumors were gone in about 3 months after starting the Tarceva and I want them to stay away as long as possible. I'm really scared to reduce the dosage. I think I'm fine on the 150 mg dosage, I work full time daily and feel good. The side effects have been bearable (except when the head sores got so bad). Has anyone else had their dosage reduced? I go to see the oncologist and have a scan in a week.