Hi, I have the same cancer as your husband. I had most of my colon taken out and it has spread to my liver in to spots also. I am going to have surgery on Aug 25th. I am receiving the same chemo as your husband but I take 1 tablet of Sandoz Ondansetron and 2 tablets of Dexasone 1/2 hr before treatment. I have not been sick at all and I have had 4 treatments. I also keep taking the Dexasone till Wednesday morning. I take one every night and first thing in the morning. My treatments start on a monday and end on a wednesday. I take the chemo out at home on wednesday. The only thing that I have had that is weird is that I can not drink or eat anything cold. Hope this helps.