Hello, I had colon cancer in June of 2004 and had folfox 4 chemo treatment. The oxaliplatin is
what causes the reaction to cold. For at least 7 days following chemo, he will have a severe reaction to cold. I could not hold a piece of cheese from the frig in my hand. You can drink nothing cold. I do not think he will be able to work that week as he cannot handle cold glasses, beer, etc. If he gets neuropathy in his hands and feet, it will feel like tingling and my feet were constantly cold. This did stop several months after the chemo stopped. One of the worse things about this type of chemo is the horrible taste in your mouth. Finding food I could tolerate wasn't easy. The other thing that I will warn you about is a side affect to the lungs. Less then 1% of the people in the world on this chemo gets pulmonary fibrosis. If your Dad starts with a dry hacking cough, TELL YOUR DOCTOR IMMEDIATELY. I told mine and he said it had nothing to do with the chemo, but it DID. I ended up in the hsospital 6 weeks following chemo because I couldn't breathe. I was on oxygen 24/7 for almost a year. I could not do anything for myself as I would get to out of breath. I am now using oxygen only when I exert myself. I am so much better then I was a year ago. I could have died from this too. I will never be 100% again, but I have learned to live with this ailment. I was on prednisone for over a year and got diabetes and osteoporosis from it. I hope this has helped you.