I finished 6 rounds of Taxol at the end of November. My numbness appeared in my fingers and toes. While my hands have returned to normal, my toes, especially my big toes, continue to have numbness. Here's the weird thing; When my two big toenails started to become discolored and thicker in appearance, I was sure I had developed a nail fungus. When one of the nail started bleeding, I called my doctor. As it turns out, this is a symptom of the Taxol. I'm going to eventually lose the toenails, and have the same thing starting on my thumbnails. Have you or anyone else had this?