I too, have had Taxol/Carb for chemotherapy. I had to have 4 months of chemo after lung cancer surgery. My oncologist said we were going to use agressive measures which meant a full day on an IV once a month. After, my last treatment, I have developed neuropathy in my toes but my fingers seem to be okay. Like you, I also have developed a hard yellow toenail on my big toe on my right foot. I thought it was fungus. It's really uncomfortable to walk alot because it feels like fine gravel in my socks. It's also uncomfortable to sleep when the sheets and blankets rest on my toes. Is this normal? Does anyone know if ibuprofen helps? I thought this would go away. It's been three months (After reading the other messages, I guess not).