I have just completed my 5th monthly 5-day chemo treatment for colon cancer and am expecting to receive the treatments for at least 7 more months. After each treatment I receive 480 mcgs of Nuepogen injected daily for 10 days. I have been experiencing tremendous weight and appetite loss, and saliva build-up between chemo treatments which do not let up until just a very few days before the next scheduled treatments, hardly enough time to regain the weight loss. I'm wondering if these symptoms might be a side effect of the Neupogen injections and would like to hear from anyone who has had this or a similar experience with Neupogen and what, if anything, was done to remedy the situation.