My husband was diagnosed in 12/o5 with this horrible disease..He had lung cancer in 1994 and was cured. now this shows up..they said there was some portal vein invasion, but no lymph node invasion..it is in the head of the pancreas..he has had gemzar with no luck...then zeloda and avastin 2 rounds...has been on nothing for about 3 weeks..have found a clinical trial at mayo that looks promising and it looks like he meets the criteria..will check with his oncologist today.. we are not ready for hospice just yet..have to try everything available first...Does anyone have any experience with the mayo clinic in minnesota...couldn't get into trial here, because they couldn't get the cancer sample they needed..it had to be clean of any tissue, cancer cells only...they did two biopsies, still couldn't get pure sample..he has copd and diabetes, so he couldn't get the whipple surgery... been married 26 years..this is the hardest thing we have ever been through..why aren't there more options available???