I am trying to decide on a clinical trial or Isolated Liver Perfusion for liver mets due to colorectal cancer. Many doctors do not endorse the perfusion method. At the University of Pittsburgh - Cancer Institute -- Dr. David Bartlett has had 74% of his patients have a response to liver perfusion. It requires an extensive orpertaion using the drug Melphalan. Has anyone had this procedure or know of someone who has. Please let me know.