My father just passed from Melanoma. It's so very hard to distinguish the different recommendations that you will receive. I will just tell you what we were told. Mass General in boston doesn't believe in the IL2 treatement, they think what you go through is not worth the short time it alots. UVA was for the IL2 and said it had the best success. My father was willing to try it, but as you know everything is a waiting game and by the time we were ready to start, they discovered it in his brain. Once it is in the brain, IL2 is no longer an options. So if it something you are considering I would act fast. We would up utilizing the gamma knife and full brain radiation. If that is a path you one day encounter, it was worth the couple of months where my dad's balance did return and his seizures did diminish. I would suggest with all the different opinions you will get. Find a doctor that your father trusts and invest yourself there, because there will always be differing opinions.