I've been on Lupron, Zometa, Casodex and Thalomide since March of this year for my stage 4 prostate cancer. Although recent bone scans show no new areas of growth other than the initial areas of ribs, pelvic bone and shoulder blade, I started getting numbness in both feet 3 weeks ago. It has now spread to my fingers and has gotten much worse in my feet. My oncologist says it's the price to pay for keeping the cancer in control with the Tholidamide. Has anyone else experienced this problem?