my husband has stage 3 melanoma. we have had 2 surgeries, one was to remove the lymphnodes in his neck....5 high dose radiation treatments...and the first month's iv interferon treatments. he started shots for the remaining 11 months of required treatment on october 16. january 23 blood work showed his liver enzymes are very elevated and the oncologist took him off the interferon and has been checking his liver functions every week. they were dropping every week until yesterday and they went right back up very high even though he is off the interferon. the oncologist has taken him off his cholesterol meds and his arthritis meds now to see if that helps................can anyone tell me if this is normal?............. do you think it is all medication related?? ...........is this what happens if the melanoma spreads to the liver??? help!!