CancerCompass message board discussion started by RhoXS on 9/25/2007 http://www.cancercompass.com/message-board/message/all,16475,0.htm Sun, 07 Sep 2008 00:00:00 GMT Sun, 07 Sep 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ I am currently using Carac to treat AKs on my forehead and cheeks. This is the fourth treatment regime using Fluorouracil or an Imiquimod based product over the past 15 or so years (but first time using Carac).I do not recollect having eye irritation previously. This time my eyes are constantly dry and irritated. Nothing I cannot live with, but certainly annoying.I am hoping someone can help with the following two questions: -Is the eye irritation due to systemic effects of the Fluorouracil or is it due to Fluorouracil inadvertently going directly into my eyes?-Is there any concern for eye damage?I have a third question not related to the eye irritation:-How long, after application, does the Fluorouracil continue to be absorbed  into the skin? l typically apply Carac early in the morning after showering. Yesterday I was caught in very heavy rain and my face was essentially washed/wiped clean about four hours after applying it. At this time was the Carac still "active" or was it essentially completely absorbed? In other words, did I lose out on a days treatment by not reapplying the Carac cream afterwards? This is an incredibly useful forum. I certainly will appreciate any response to my questions.  RhoXS Tue, 25 Sep 2007 00:00:00 GMT I to had some eye irritation. It wasn't continuous, just after application and then it went away. The absorbtion time for Carac is approx 2 hours. My Doctor prefered me not to use any moisturisers at all until after my 28 days. All Doctors have different opinions. You can look at my results on my website www.myskinjourney.com Good luck jimbo61 Wed, 10 Oct 2007 00:00:00 GMT