CancerCompass message board discussion started by willa1977 on 1/11/2008 http://www.cancercompass.com/message-board/message/all,19633,0.htm Sat, 06 Sep 2008 00:00:00 GMT Sat, 06 Sep 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Hi,My husband had a prostate biopsy 1 year ago and the results indicated that he had no cancer; however, there were a couple of cores that the pathology report indicated having atpia cells. He just had another biopsy and the pathology report reads that in the right medial apex there is focal adeniocarcinoma, (not Gleason rated due to small size of tumor ?) which is not consistent with the previous reports location of changing cells. And  there is atropy in other sections with the nucleoli not enlarged.His PSA tests 1 year ago were 7.5, repeat was 8 and the FREE PSA was 10 and the most recent is 10.5. What should he do next about treatment, he wants to do the "WATCHFUL WAITING"Help please, thank-you willa1977 Fri, 11 Jan 2008 00:00:00 GMT Recent more extensive screening  has resulted in most men now being diagnosed with early stage cancers, which has raised the subjects of gray areas, over diagnosis, over treatment, and insignificant tumors.None of the PC tests will always give the clear cut black and white results we would all prefer. That includes biopsy readings which are ubjective. For that reason you could request a 2nd reading of these biopsy slides, or of any future biopsy.Theree's a lot of information available about "active surveillance" as it's now called. Usually lifestyle changes, including exercise, diet and supplements are implemented along with close checks.Johns Hopkins and others have published criteria for that approach, and there's also information available about it and other treatment options from other places including the yananow.net site, and prostatecancerwatchfulwaiting.co.za, .  Johnw100 Sat, 12 Jan 2008 00:00:00 GMT With a high PSA, he should have it repeated every six months. The rate of increase is also a sign of possible prostate cancer and whether another biopsy is necessary. I'm sure your insurance will pay for it and I don't understand why the urologist didn't repeat it already. Another informative site that helped me understand all of the in's and out's is yannanow.net or yananow.net. When you watchful wait, just make sure you are looking through a magnifying glass not sunglasses. Linb1414 Thu, 17 Jan 2008 00:00:00 GMT