CancerCompass message board discussion started by luckykl on 2/23/2008 http://www.cancercompass.com/message-board/message/all,21262,0.htm Tue, 07 Oct 2008 00:00:00 GMT Tue, 07 Oct 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Hi! My uncle was diagnosed with light chain myeloma, to be exact lamda chain. He was first treated with thalidomide (2months)/ iv.velcade (6 months). His oncologist decided he was a good candidate for a autologous stem cell transplant. He received melphalan/dex to prep him for transplant. His cancer was is remission for less than 1 year after receiving the transplant. He his now at the end of the second round of chemo, I.v Velcade/Revlimid. The Md has given him a very poor prognosis at this point. The cancer has been very progressive since his relapse. He is in a great deal of pain and having trouble with ambulatory tasks. I guess I am just asking if anyone has any information on other forms of therapy in that this form of multiple myeloma is so rare. It has been roughly just over 2 years since he was first diagnosed and he is not ready to give up the fight! luckykl Sat, 23 Feb 2008 00:00:00 GMT  Craig just posted an audio on the latest findings today you might want to download it, very interesting. MMS On 2/23/2008 luckykl wrote:Hi! My uncle was diagnosed with light chain myeloma, to be exact lamda chain. He was first treated with thalidomide (2months)/ iv.velcade (6 months). His oncologist decided he was a good candidate for a autologous stem cell transplant. He received melphalan/dex to prep him for transplant. His cancer was is remission for less than 1 year after receiving the transplant. He his now at the end of the second round of chemo, I.v Velcade/Revlimid. The Md has given him a very poor prognosis at this point. The cancer has been very progressive since his relapse. He is in a great deal of pain and having trouble with ambulatory tasks. I guess I am just asking if anyone has any information on other forms of therapy in that this form of multiple myeloma is so rare. It has been roughly just over 2 years since he was first diagnosed and he is not ready to give up the fight!  mmsurvivor Tue, 26 Feb 2008 00:00:00 GMT Hello there,My mother has Bence Jones Myeloma/ Light Chain Myeloma. At the moment she has had VAD, Stem Cell transplant, Thalidamide (which was ceased due to severe constipation) now they are waiting on Velcade. She was admitted today with Kidney Failure and her Bence Jones has increased to 8. That is very high for mum. So they have started her on a high dose of Dex as well as Morphine. She looks good but this nasty cancer can be invisible to others.I have asked about her prognosis and was advised that the kidney damage can be reversed. If not then dialysis is an option. Feel free to ask me questions I will be more than happy to help if I can..Melanie  melanie and carol Fri, 14 Mar 2008 00:00:00 GMT So sorry to hear about your mother. I hope that her kidney damage can be reversed. That really makes treatment a bit tricky :( My uncle finished his last round of velcade and revlimid about a month ago. His cancer did not respond in fact his numbers have doubled. The doctor told us the best he could do was buy some more time. There have been talks of undergoing some heavier and more intense chemotherapies and perhaps radiation. He had a stem cell transplant just about a year and half ago. He relapsed after only 9 months. I have been doind research and it seems so many therapies exclude this lamda light chain form of myeloma. It is so rare. My prayers are with everyone that is going through this and of course the family members who are helping them along the way. Thank you for your response. luckykl Tue, 18 Mar 2008 00:00:00 GMT Hi there,Mum is out of hospital with and her kidney function has improved. I will keep my fingers and toes crossed that Velcade will work...Thanks and take care  melanie and carol Tue, 18 Mar 2008 00:00:00 GMT