CancerCompass message board discussion started by cso#19 on 4/27/2008 http://www.cancercompass.com/message-board/message/all,23471,0.htm Mon, 01 Dec 2008 00:00:00 GMT Mon, 01 Dec 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Anyone using  Clopramine-its prescribed use is for anti depression, however this article says some brain tumor patients have had success using this med to penitrate the blood brain barrier to cut off the tumor. Could this be used in addition to Temador?http://virtualtrials.com/news3.cfm?item=4204 cso#19 Sun, 27 Apr 2008 00:00:00 GMT  On 4/27/2008 cso#19 wrote:Anyone using  Clopramine-its prescribed use is for anti depression, however this article says some brain tumor patients have had success using this med to penitrate the blood brain barrier to cut off the tumor. Could this be used in addition to Temador?http://virtualtrials.com/news3.cfm?item=4204 Hello everyoneI know a lot about this as I’ve researched it myself for my mother.  I tracked down the professor responsible for the discovery (Professor Pilkington -  Professor of Cellular & Molecular Neuro-oncology, Director of Research, School of Pharmacy & Biomedical Sciences, University of Portsmouth) and have included links here, one of which is about our famous cricketer, Alan Igglesden, who had an inoperable brain tumour and is still here 10 years later with this anti-depressant). If I can post PDFs here I have info from him on the science behind the use of tricyclic drugs such as Clomipramine & Nortriptyline in inducing programmed cell death (apoptosis) in brain tumour cells. Each tumour tends to have a variety of different cells, each of which may have a different response to the treatment agent – in the trials they witnessed some patients with a good quality of life as long term survivors when given only months.  As with all these sorts of things, there is no money in this drug it’s been around 40 years as an anti-depressant and without big money invested to run trials, these wonderful discoveries get frustratingly put on hold.  But they are there and they work and sometimes ‘anecdotal’ is enough …. Especially when it is even covered by our national TV station British Broadcasting Corporation and in our respected newspapers like The Independent etc.  I hope this helps everyone.Dose should be worked up 25mg first 4 days, 50 mg next four etc until taking approx 125mg a day.http://www.port.ac.uk/brainlab http://news.bbc.co.uk/2/hi/health/4066593.stm I hope this helped you, Clared/o Judy 57 y/o 1995 right lobe tennis ball sized oli with headaches, seizures …  resected, full whack radiotherapy then no recurrence or treatment for 12 YEARS!Sep 2007 After a couple of years ‘clumsy’ falls dx 3cm/3cm inoperable astrocytoma Grade II with left sided paralysis, October 2007 Temodar 5 days in November 2007 walking again, December 2007 clear MRI – miracle – tumour no longer seen?? January 2008 fell broken spine and very big with lymph swelling, left sided paralysis again, March 2008 MRI, tumour back 4cm/4cm, March 2008 started Poly-MVAMarch 2008 2nd round of chemo 5 days/21April 2008 3rd round of chemo 5 days/21 can move left side again and balance but difficulty walking as muscle atrophy from decadron and being in bed while spine mended … 2 weeks later April 2008 is walking again now with a frame, speech perfectSupplements:  Poly-MVA, Shark Liver Oil, Astragalus, Green Tea Extract, lots of dark red/black grapes, Noni juice, Fish Oil, Curcumin, Barley pills, Bromelain, Beta Glucan ….    Will start Clomipramine at 125mg a day Looking for quality Boswellic Acids supplement, have just bought PSK mushroom extract, and thinking about doing Ruta 6 protocol clarejoanne Mon, 28 Apr 2008 00:00:00 GMT