CancerCompass message board discussion started by Sam38 on 4/29/2008 http://www.cancercompass.com/message-board/message/all,23532,0.htm Mon, 01 Dec 2008 00:00:00 GMT Mon, 01 Dec 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Has anyone experienced a major change in their GBM?  3 weeks hubby was driving shooting pool and out and about and boom MRI shows growth 2nd one contradicts the previous one but now he has lost his right half of his vision in the right side of both eyes, slurring speech, hoarse from the new dose of 32mg per day of steroids and can only whisper, lost the use of the right side of the body, has become incontinent overnight literally, unable to walk, and in a wheelchair within the last 10 days but today now the left side the good side is giving out.  MRI mentioned a PONS anyone have any ideas what to try ?RX with Temodar 2-07 to 7-07 then 7-07 to 12-07 Avastin with CPT11 then 1-08 to 2-08 Avastin with VP16 now back on Temodar nightly 100mg with Rapamycin 5 mg nightly with Zofran.  But huge deficits occurring within the last 3 weeks out of no where.  Bless us all!        Sam38 Tue, 29 Apr 2008 00:00:00 GMT Oh Sammy, things just don't sound good.   What is it that they are saying about this PONS?  I don't know anything about that.I'm sorry.Wishing you peace and strength.Barb  bpanc Tue, 29 Apr 2008 00:00:00 GMT