CancerCompass message board discussion started by Gct2-brenda on 5/1/2008 http://www.cancercompass.com/message-board/message/all,23613,0.htm Sun, 06 Jul 2008 00:00:00 GMT Sun, 06 Jul 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ I am scheduled for surgery on May 15th, 2008 to remove 1 large and 2 small Granulosa Cell Tumours. This is my third surgery for GCT - the first in 2002 with complete hysterectomy (1 tumour), a second surgery in January 2007 (4 large tumours), and now a third surgery. No chemo prior to this as my Oncologist says that GCT appears to be resistant to treatment (both chemo and radiation). Because the tumours have returned so quickly this time, he is suggesting either bleomycin etoposide and platininum BEP or carboplatin and Taxol. The latter sounds less toxic .....Just wondering if anyone out there has had treatment for GCTs (other than surgery), what combination, and what result ....Thanks Gct2-brenda Thu, 01 May 2008 00:00:00 GMT  On 5/1/2008 Gct2-brenda wrote:I am scheduled for surgery on May 15th, 2008 to remove 1 large and 2 small Granulosa Cell Tumours. This is my third surgery for GCT - the first in 2002 with complete hysterectomy (1 tumour), a second surgery in January 2007 (4 large tumours), and now a third surgery. No chemo prior to this as my Oncologist says that GCT appears to be resistant to treatment (both chemo and radiation). Because the tumours have returned so quickly this time, he is suggesting either bleomycin etoposide and platininum BEP or carboplatin and Taxol. The latter sounds less toxic .....Just wondering if anyone out there has had treatment for GCTs (other than surgery), what combination, and what result ....ThanksHi  I have not had chemo, however I have a question for you.  After your total hysterectomy and 2nd surgery ( or really Before)...what were your symptoms?  I had a totoal hys. this year and removed one tumor and hopefully I'll know what to pay attention to.  Prior to my diagnosis, I bled for a couple years pretty consistent, so with the hyst. I obviously wont bleed.  I'm sorry I cant offer an answer to your question.Take care and God Bless youSusieB   SusieB Mon, 05 May 2008 00:00:00 GMT  On 5/5/2008 SusieB wrote: On 5/1/2008 Gct2-brenda wrote:I am scheduled for surgery on May 15th, 2008 to remove 1 large and 2 small Granulosa Cell Tumours. This is my third surgery for GCT - the first in 2002 with complete hysterectomy (1 tumour), a second surgery in January 2007 (4 large tumours), and now a third surgery. No chemo prior to this as my Oncologist says that GCT appears to be resistant to treatment (both chemo and radiation). Because the tumours have returned so quickly this time, he is suggesting either bleomycin etoposide and platininum BEP or carboplatin and Taxol. The latter sounds less toxic .....Just wondering if anyone out there has had treatment for GCTs (other than surgery), what combination, and what result ....ThanksHi  I have not had chemo, however I have a question for you.  After your total hysterectomy and 2nd surgery ( or really Before)...what were your symptoms?  I had a totoal hys. this year and removed one tumor and hopefully I'll know what to pay attention to.  Prior to my diagnosis, I bled for a couple years pretty consistent, so with the hyst. I obviously wont bleed.  I'm sorry I cant offer an answer to your question.Take care and God Bless youSusieB Hi,I also had surgery 6 weeks ago to remove a larger GCT that was cancerous. Luckily it did not spread.  I had a completer Hysterectomy and Lymph Nodes removed.The only sigh I had before they spotted the tumor was wierd bleeding for a year or so too.  I am also curious what symtoms if any Brenda had with 3 surgerys now.I am being told no Chemo is necessary and to have bld tests and a CT scan every 6 months.Take care of yourself,Patti  Patti 123 Wed, 07 May 2008 00:00:00 GMT  On 5/1/2008 Gct2-brenda wrote:I am scheduled for surgery on May 15th, 2008 to remove 1 large and 2 small Granulosa Cell Tumours. This is my third surgery for GCT - the first in 2002 with complete hysterectomy (1 tumour), a second surgery in January 2007 (4 large tumours), and now a third surgery. No chemo prior to this as my Oncologist says that GCT appears to be resistant to treatment (both chemo and radiation). Because the tumours have returned so quickly this time, he is suggesting either bleomycin etoposide and platininum BEP or carboplatin and Taxol. The latter sounds less toxic .....Just wondering if anyone out there has had treatment for GCTs (other than surgery), what combination, and what result ....Thanks Hi Brenda--My name is Kathy-- I am a 5 year survivor of GCT.  I had a fantastic GYN.onc. in Clearwater, Fl. who removed a 35 pound tumor in 2003.  I lost about 60 pounds, and my hair.  I had the combination of bleomycin, etoposide and cisplatin for a 12 week course.  five days on and then two weeks rest.  They gave me Kytril and Zofran for the nausea and it worked fantastically for me.  The biggest side effect from the chemo is peripheral neuropathy in my hands and feet (they feel like pins and needles) but the neurologist has prescribed Lyrica for that and it works wonders.  I feel good enough to work part-time, and have a very rewarding life now.  I hope this helps.  Good luck on your surgery, and may you do as well as I did.  Please let me know what happens.  Kathy KH2905 Thu, 15 May 2008 00:00:00 GMT Kathy .... Thanks for responding. Were you given a stage with a tumour of 35 pounds? That is huge! And congrats on being cancer free for 5 years!!It is nice to know that there is treatment for the pins and needles. I have noticed this as a side affect in some of the articles I have read and having experienced the feeling before for short periods when sleeping too long on an arm, I certainly would not want to be 'burdened' with it on a continuous basis. I am so glad the meds work for you!! My surgery is behind me now and other than the normal discomfort of having a huge incision, I am recovering quickly and feeling great. My oncologist will contact me in the next few weeks once he receives the report from the lab and we will decide then whether chemo will be our next step. He was very pleased with the results of the surgery, so I'm hoping that we might skip adjuvant treatment once again ...... Thanks again for sharing and all the best to you for a healthy and GCT-free life!!Brenda Gct2-brenda Sun, 25 May 2008 00:00:00 GMT