CancerCompass message board discussion started by KB1263 on 5/5/2008 http://www.cancercompass.com/message-board/message/all,23775,0.htm Thu, 24 Jul 2008 00:00:00 GMT Thu, 24 Jul 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Hello Everyone,I haven't posted in awhile, but my husband has been doing pretty well on the CPT11/Avastin regimen.  Now his doctors are adding Temodar back to his schedule, as well.  He's taken these chemos separately and has done well with them, but we're not sure what to expect with them being given together.  This could definitely be the one, two punch with a kick in the gut.  Has anyone had this same type schedule?  If so, how did it go? KB1263 KB1263 Mon, 05 May 2008 00:00:00 GMT I'm starting this regimine tomorrow. Fingers are crossed for all of us! Sunflower13 Tue, 06 May 2008 00:00:00 GMT  My husband dx 11/07 course of treatmentPartial resection of gbm left temporal loberadiation / Temadar / AvastinHas some minor defecits since surgery and has experienced some minor problems with Temadar such as skin problems, but doing very well. "stabel" mri's with slight improvement.   Laura412 Tue, 06 May 2008 00:00:00 GMT I'll be curious to see how this goes. If I understand what you say - they are going to use BOTH the CPT11 and the Temador?My brother has done well with the Avastin/CPT  - so far - so good.  It shrunk considerably after the first cycle and now seems to be stable with very slight schrinkage after each subsequent cycle. He just began his 5th cycle and the ocon wants to put him through 9 total treatments.Eileen  Wissis Tue, 06 May 2008 00:00:00 GMT Yes, he's doing both CPT-11 and Temodar at the same time.  It sounds like a lot, and I'm certain it is.  However, our doctor is taking the proactive approach.  He says he's going for the cure!!  This certainly gives us hope, but I just worry what it will do to my husbands overall health.  He has also done quite well on the CPT-11/Avastin, but adding the Temodar is a different thing.  We're just one day into the Temodar.  We've got the rest of this week to go.  Say a prayer for him. KB1263 KB1263 Tue, 06 May 2008 00:00:00 GMT doc's at Duke put my patient on this and he has declined and literally within 3 mo's is in the dying process we had to put him in the hospital today.  I pray that this mix that they did for him doesn't cause the evil tumor to grow--I think it has grown exponentially Sam38 Wed, 07 May 2008 00:00:00 GMT  On 5/5/2008 KB1263 wrote:Hello Everyone,I haven't posted in awhile, but my husband has been doing pretty well on the CPT11/Avastin regimen.  Now his doctors are adding Temodar back to his schedule, as well.  He's taken these chemos separately and has done well with them, but we're not sure what to expect with them being given together.  This could definitely be the one, two punch with a kick in the gut.  Has anyone had this same type schedule?  If so, how did it go? KB1263 Hi, I was just wondering how this treatment is going?  My father started treatment 2 weeks ago of daily temodar while undergoing IMRT.  Last week he started a once a week dose of CPT-11 as well.  We were hopeful, as our dr has a pretty good track record with this plan, but my dad has developed some pretty serious side effects from the temodar.  Constipation, nausea, vomiting.   He has lost 11 pounds and cannot each much of anything, so they are taking him off of both chemos for a week to see how he responds.He was diagnosed with GBM 4/29/08, had at 90% resection.  Was recovering well until he developed a severe allergic reaction to dilantin while being weaned off and on to keppra.  He also developed blood clots that settled in his lungs.  He is now on zonegran for anti-seizure.   this disease is so sad.  He never had any health problems until this happened.  We were so hopeful starting out to control this, but it seems as though he has had one reaction after another.  It is terribly frustrating. Adam Tobex Thu, 12 Jun 2008 00:00:00 GMT