CancerCompass message board discussion started by howtocope on 6/16/2008 http://www.cancercompass.com/message-board/message/all,25088,0.htm Sun, 23 Nov 2008 00:00:00 GMT Sun, 23 Nov 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Please advise if you have had a similar experience.  My father was recently diagnosed w/ cancer of unknown primary, w/ mets in the liver and mets in the lungs.   He had a recent colonoscopy/endoscopy that was clean, but had one in the summer of 2007 that led to a follow-up colonoscopy in November 2007, which resulted in the removal of large polyps that were supposedly benign.  This immediately preceded the onset of his symptoms. The doctors who had been seeing him wanted to start him on chemo w/ drugs that attack colon cancer, but we are having a difficult time understanding this recommendation.  Is it possible that he could have colon cancer with a clean colonoscopy?  (Perhaps, even that the polyps that were removed before could have been his primary cancer?)  We are perplexed and trying to figure this all out, and would be grateful to know whether anyone has ever traced Stage 4 cancer to "benign" polyps that later turned out to be cancer. howtocope Mon, 16 Jun 2008 00:00:00 GMT Hello Howtocope,I don't know about the polyp issue, but it is possible to have cancer on the outside of the colon which would not show up on colonoscopy.  Good luck to you both.Lynn 2ndtimer Tue, 17 Jun 2008 00:00:00 GMT