CancerCompass message board discussion started by Concerned Mom on 11/20/2006 http://www.cancercompass.com/message-board/message/all,7905,0.htm Sat, 11 Oct 2008 00:00:00 GMT Sat, 11 Oct 2008 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ I have written here before, under Concerned mom in the Leukemia section (symptoms listed there), it was asked what my sons last blood work stated and I have some questions. This was when he was tested for Celiac disease 04/24/06. The doctor said that everything was fine. I requested a copy to be mailed to me a week ago to the new town I live in and this is what some of the test results said: Eosinophils % 4.1 flagged High Sed Rate (ESR) 16 also flagged High HLA-B27 was positive 258 and the doctor wrote on the side that rises in multiple myeloma, uncommon younger that 40 years old Some of the other ones on his CBC with Auto Diff were on the high end of the normal range. I am very concerned now because of what these test showed and the fact that nothing was followed up especially with all of the symptoms he has presented with. Can anyone help me with this. Should I be concerned or is that part okay at his age (10 yrs old)? The others that were on the hight end were his WBC, RBC, MCHC, Hemoglobin. Thank You Concerned Mom Mon, 20 Nov 2006 00:00:00 GMT it is actually under I am concerned about my son in the Leukemia section.. Sorry Concerned Mom Mon, 20 Nov 2006 00:00:00 GMT HLA-B27: People who are positive for HLA-B27 are at higher risk for certain autoimmune diseases including ankylosing spondylitis, Reiter's syndrome, certain eye disorders such as acute anterior uveitis, iritis, psoriatic arthritis and inflammatory bowel disease. Just because a person is HLA-B27 positive does not mean they will get any of those diseases, they are just at higher risk. I find no references that HLA-B27 has anything to do with multiple myeloma. Eosinophils 4.1% - To me this does not seem high. I have always thought the normal range was 0-5%. Eosinophils do lots of things such as fight viruses and parasites, but they are best known for allergic reactions such as asthma. ESR 16 - To me this does not seem high. The normal range varies a little based on age and sex, but it is commonplace to see numbers between 0 and 15. ESR is a nonspecific indicator of inflammation. It says there is inflammation somewhere. It does not say where nor why. 16 does not seem high to me. If your doctor is worried he can do a slightly more specific test called a C-Reactive Protein (CRP). When a page or two of blood tests are done on normal people, there are always a handful of numbers out of the normal range. It is extremely rare that anyone has a page or two of numbers that are fall into the normal range. Call your own doctor and ask for a copy of the last 10 pages of bloodwork done on you - do not be surprised to see a handful of numbers outside the normal range as well. On a separate note, keeping good health records of yourself and your family at home in folders is a good idea. That way you can compare previous bloodwork or other tests with current bloodwork yourself. For example, if your husband's PSA is normal (0-4) last year and this year but the number went from 0.4 to 3.4, that is something to worry about. Amnia Mon, 20 Nov 2006 00:00:00 GMT Thank you for your information, that is definately a relief. I have just been so worried about him with all of these symptoms that I guess any little thing out of the ordinary puts a red flag in my head and I start jumping to conclusions. Maybe all of the symptoms he is having are not related or maybe they all lead to something not as severe as my mind thinks they are. Does that make sense? I know that as soon as I can get some sort of insurance for the family, and get him checked out head to toe I will feel a lot better. Thank you for responding so promplty, I'll sleep better tonight. God Bless you! Concerned Mom Mon, 20 Nov 2006 00:00:00 GMT