Gdpawel's Recent CancerCompass Activity

  • Gdpawel has replied to a post on the message board

    Robert A. Nagourney, M.D.Oncologists confront numerous hurdles as they attempt to apply the new cancer prognostic and predictive tests. Among them are the complexities of gene arrays that introduce practicing physicians to an entirely new lexicon of terms like “splice variant, gene-rearrangement, amplification and SNP.”Although these phrases may roll of the tongue of the average molecular biologists (most...

    September 03 at 1:23 AM view post
    • Gdpawel has created a new message board discussion

      Mark Pegram, M.D. The use of cutting-edge technology and bioinformatics to inform clinical decision-making in oncology is still a ways off, according to Mark Pegram, MD, the Susy Yuan-Huey Hung Professor of Oncology and Director of the Stanford Breast Oncology Program, Stanford University, Palo Alto, California. At the 9th Annual New Orleans Summer Cancer Meeting, Dr. Pegram said the “lofty goal” of targ...

      September 02 at 11:30 PM view discussion
      • Gdpawel has replied to a post on the message board

        http://cancerfocus.org/forum/showthread.php?t=3320 http://cancerfocus.org/forum/showthread.php?t=3905 http://cancerfocus.org/forum/showthread.php?t=4073

        August 20 at 2:38 AM view post
        • Gdpawel has replied to a post on the message board

          MCED explains why glioblastoma (the most common primary brain tumor) patients who have favorable responses to bevacizumab (Avastin) develop early calcifications in the tumor bed while glioblastoma patients with poor responses to bevacizumab do not develop calcifications.”http://www.vasocell.com/MCED_Home.htmlMCED Discoveryhttp://www.vasocell.com/MCED_Discovery.html

          July 17 at 1:53 AM view post
          • Gdpawel has created a new message board discussion

            MCED: A newly-discovered mechanism of endothelial cell death Using a patented laboratory test, they have discovered a new cell death pathway in endothelial cells which is referred to as Massively Calcified Endosomal Death (MCED). Exploitation of this pathway may afford an effective approach to the treatment of cancer and to the prevention and treatment of atherosclerotic vascular disease, heart attack, and strok...

            July 15 at 4:36 PM view discussion
            • Gdpawel has created a new message board discussion

              In targeted gene therapy - the targeted gene or "driver" oncogene - doctors use a therapy that works on just one gene, then it's possible for tumors to shrink. Unfortunately, those tumors will eventually find a way to subvert that gene. There is some twelve main gene signaling pathways in cancer. Gene signaling is part of a complex system of communication that governs cellular activity and coordinates cell action. I...

              March 03 at 8:46 PM view discussion
              • Gdpawel has replied to a post on the message board

                I’ve been researching cell function analysis for the last 12 years, and even during that period, I’ve come across the resistance mechanism from the so-called trialist system, time and time again. I’ve researched the history of this apprehension; one example coming from NCI’s feeble attempt to study assay-directed therapy of lung cancer some years ago.The study was a failure because it was done...

                March 03 at 8:41 PM view post
                • Gdpawel has replied to a post on the message board

                  Would it be safe to say that one of the reasons medical oncologists don’t like in vitro chemosensitivity tests is that it may be in direct competition with the randomized controlled clinical trial paradigm – a fiercely defended relic of our ignorance? Cell culture assays measure the “efficacy” of anti-cancer drugs. The randomized clinical trial measures the “efficacy” of anti-cance...

                  March 03 at 8:40 PM view post
                  • Gdpawel has replied to a post on the message board

                    Robert Nagourney, M.D.In human experience, the level of disappointment is directly proportional to the level of expectation. When, for example, the world was apprised of the successful development of cold fusion, a breakthrough of historic proportions, the expectations could not have been greater. Cold fusion, the capacity to harness the sun’s power without the heat and radiation, was so appealing that people r...

                    March 03 at 8:39 PM view post
                    • Gdpawel has replied to a post on the message board

                      Replies to comments regarding personalized cancer treatment, as published in the December 15, 2013 "ASCO Post" (American Society of Clinical Oncology publication).By Larry Weisenthal, MDDecember 15, 2013, Volume 4, Issue 20Dr. Mason states that I implied that Dr. Telli supports the routine application of chemosensitivity assays. I have no knowledge regarding Dr. Telli’s views on this subject, nor did I in any w...

                      February 20, 2014 view post
                      Load more activity
                      Loading more activity

                      About Gdpawel

                      Caregiver, Researcher
                      Ovarian Cancer
                      Cancer Treatments, Chemotherapy, Clinical Trials and Research, Conventional Treatments, Genetics, Radiation, Side Effects, Supplements, Surgery

                      I've been involved with internet cancer research for 17 years, since the days of the CompuServe Cancer Forum which involved many professionals including medical oncologists who were fascinated with this new tool for sharing ideas. I made many contacts with leading oncologists from around the country and learned a great deal regarding new developments in the treatment of cancer.

                      You are most welcome to peruse the non-afilliated, PhD-oriented cancer information website I've been the moderator for 7 years. My 12 years studying cell function analysis, which holds no boundaries across the various cancer types, makes it a perfect place for me to continue my already years of internet cancer research.


                      We care about your feedback. Let us know how we can improve your CancerCompass experience.