Research Suggests Treatments May Prevent Removing Larynx in Advanced Laryngeal Cancers

by: cancercompass

University of Michigan Health Systems announced recent research that may help preserve the larynx in advanced laryngeal cancers.

Cancer patients with large tumors on their larynx often have the organ removed, causing them to lose their voice, say University of Michigan Health System researchers.  They've performed a new study that suggests one round of chemotherapy could help doctors decide whether avoiding surgery is a plausible option.

This study specifically analyzed advanced laryngeal tumors of 36 patients previously studied in two advanced larynx cancer studies conducted by the university.  Those patients were given one round of induction chemotherapy to see if their tumors responded. If the tumor shrank by 50% after this first round, they were given three more rounds of chemotherapy treatments along with daily radiation therapy.

Overall findings suggest most patients (81%) responded well to the induction therapy. Three years after treatment, 78% were alive and 58% still had an intact larynx.  

Results of the study appear online in the journal Laryngoscope.

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