Study Results of Metformin's Effects on Diabetic Breast Cancer Patients

by: cancercompass

Previous studies have suggested metformin - a drug used to control diabetes - helps diabetic breast cancer patient survival rates. A new study from doctors at the University of Texas, M.D. Anderson Cancer Center provides additional clinical data that tests the drug's efficacy in diabetic breast cancer patient treatments that include neoadjuvant chemotherapy.

The study, published recently in the Journal of Clinical Oncology, measured the pathologic complete response (pCR) rates in 2,529 early-stage breast cancer patients, 68 of which were diabetic and taking metformin and 87 diabetic patients not taking metformin.

Measuring pCR rates is one way doctors can test a drug's efficacy in patients. When these rates are high that usually indicates a higher likelihood the drug itself is working.  

During this recent M.D. Anderson study, researchers discovered higher pCR rates in diabetic breast cancer patients taking metformin than diabetic breast cancer patients not taking the drug.

Researchers say further study is warranted to determine the potential of metformin as an anti-tumor drug.

Has diabetes affected your breast cancer treatment? Share your experiences at the CancerCompass Breast Cancer Message Board.