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Grade is a measure, from one to four, of the degree of abnormality of cancer cells in comparison with normal cells. Lower grade cancer cells more closely resemble normal cells, and are usually less aggressive.

Genetic refers to hereditary information which is stored in the DNA and passed down from generation to generation. Grade is a measure, from one to four, of the degree of abnormality of cancer cells in comparison with normal cells. Lower grade cancer cells more closely resemble normal cells, and are usually less aggressive.

Graft-versus-host-disease (GVHD) is a common side effect after a stem cell or bone marrow transplant from a donor. It occurs when the transplanted immune cells recognize your body as foreign and attack your cells. The symptoms of GVHD can range from mild to life-threatening, and can often be managed using immunosuppressive drugs.

Graft-versus-tumor (GVT) effect is a beneficial side effect of graft-versushost-disease (GVHD), occurring after a stem cell transplant from a donor. When the transplanted stem cells recognize the recipient's body as foreign, they also attack any cancer cells that still remain after treatment. This can be curative in some cases, and may also reduce the risk of a recurrence.

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