Allergic To The Best Cancer Drug? Doctors Offer Possible Way To Keep Taking It

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Having a bad reaction to penicillin as a child doesn't guarantee you're still allergic decades later. And if the oncologist says you have to switch chemotherapies because of an allergic reaction, well, maybe not.

 

3 Comments

Wed Apr 14, 2010 11:39 PM

Super encouraging.  I had reactions to carboplatin 3 times, beginning with my 10th round,including two during desensitization.  I didn't show improvement but who knows if perhaps I would have with more doses and time spent slowly building up the trmt. time.  I think the protocol needed adjusting such that I got higher doses of benadril closer to the time more of the carbo was being given.

Thu Apr 15, 2010 04:06 AM

I also became allergic to carboplatin at the 8th treatment. After several ovarian cancer recurrences, I tried it again because of the number of years that had passed. I tolerated one treatment, then had allergic reaction on the second. A nurse told me about trying desensitization and since I have an immunology background, I researched the subject and found a paper that described the protocol and another that recounted the cases of two women who still did not tolerate the 6 hour protocol. For them, the time of infusion for each dose was increased. One required a 24 hour protocol and the other a 72 hour protocol. In each case, the woman was able to continue being treated by using the protocol specific for her. My case has been similar. I need to receive each dose over ~6 hours and a one hour break between each dose. I have had 4 successful treatments using the longer protocol.

Thu Apr 15, 2010 05:08 AM

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