NSCLC

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NSCLC

by kts123 on Thu Jul 20, 2017 06:08 PM

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Hi, my father in law (an ex smoker aged 72) has recently been diagnosed with:

NSCLC T2a N2 M1b adenocarcinoma (TTF1 and Napsin negative) with a solitary adrenal matastasis. Molecular testing results were EGFR and ALK negative and PDL1 less than 1%.

The NHS have told that us that he is not suitable for oral target therapies or immunotherapy and have so far given him 2 rounds of chemotherapy ( Cisplatin and Pemetrexed).

I wondered if anyone could point me in the right direction for looking at other private therapies that may be suitable. I have had info from a company called Oncologica who offer a biopsy test for matching tumours to specific target therapies. Any advice would be greatly appreciated as its a minefield out there!! 

Many thanks x

RE: NSCLC

by Devalzadvok8 on Fri Nov 10, 2017 06:59 PM

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kts123,

"NSCLC T2a N2 M1b adenocarcinoma (TTF1 and Napsin negative) with a solitary adrenal matastasis. Molecular testing results were EGFR and ALK negative and PDL1 less than 1%.

The NHS have told that us that he is not suitable for oral target therapies or immunotherapy and have so far given him 2 rounds of chemotherapy ( Cisplatin and Pemetrexed)."

More info needed.  Father on Medicare, yes?  Good supplemental insurance?  Otherwise, most remaining treatment forms are unafordable by 'normal' human beings.  Is he going through 'standard' 6 session chemo, alimta/Cisplatin?  Assume a PET Scan was taken before series started?  Assume a PET Scan w/b taken after 6th session?  

While you  shouldn't let the 'grass' grow beneath your feet you still might want to wait until the ending PET Scan has been taken and review the results.  Given this late date, ( since your post ), do I assume that your father has already completed his series and received the results?  Update here from you?

Keytruda has only recently been approved for this type of cancer.  So far, is only immunotherapy drug approved for this condition.   Am on it, myself ( after 6 sessions of chemo ), but too early to judge results.  There is a short thread on Cancer Compass that may produce something in the future.  Not much in it now...........

NOTE:  Your father's 72?  Many doctors/oncology labs pretty much have you written off by this time.  If they say, "At your age......", you may want to start looking for another doctor.  Don't like the answers given?  Get a second opinion.  His life is at stake................

Rod

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