EC recurrence in the nodes ..Experiences please ?

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EC recurrence in the nodes ..Experiences please ?

by akb1972 on Sun Feb 10, 2019 11:41 AM

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We just got the devasting news of a recurrence in regional lymph nodes (thankfully, all organs are clear) - my 47 yr old hubby and father of 3 children between 9 and 21 years of age.   This has occured nearly 4 years following seemingly successful treatment (neoadjuvent chemo + radiation + esophagectomy) for (initially diagnosed) locally advanced T3N0 EC with clean surgical margins and negative nodes.  I would appreciate any and all experiences - both positive and negative - with treatment regimens for EC recurrence that is seen in regional lymph nodes with no other organ involvement other than microscopically positive adenocarcinoma cells (moderately differentiated)  in the esophagus.   I understand that most EC recurrences occur in years 1 and 2 following esophagecomy, and the survival for later stage recurrences such as ours imply maybe a slower growing cancer, or something to that effect.  But I really need to know more from all of you.   Also, if anyone has an APC gene mutation and participated in any gene therapy trials up in Boston or wherever, please be in touch as well. thank you ! 

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