Biopsy or Wait

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Biopsy or Wait

by Mikeh on Sun Nov 06, 2005 12:00 AM

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Since Oct,2000 I have had Psa test every 6 months. Tests started out around 4.3. The last Test, Oct, 2005 was 8.3. I have had 3 biopsies. all negative. I'll be seeing Dr again this month (Nov 23). Should I have another biopsy? Is there an alternative?

Biopsy and Psa

by Bill27 on Wed Nov 09, 2005 12:00 AM

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My feeling is that I would not undergo any more biopsies than "neccesary". I have not seen any data on post-biopsy PSA acceleration, but a number of men have brought it up. My PSA rose 1.2 in two years (to 4.6) then rose 1.2 in 6 months after my biopsy. My biopsy did show a small amount of cancer. Some theorize that biopsy can help the cancer expand in the prostate. This PSA curve could easily be studied and if it exists I think it raises some interesting questions i.e. does the diagnosis facilitate the disease. Scary. Something to think about, but with neg biopsies maybe the comfort is worth it.

Wait

by Oncrx on Wed Nov 09, 2005 12:00 AM

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How old are you? Have you been told a Gleason score? I see no reason for another biopsy. It sounds like you have low risk disease and depending on your age, you have several options. Watch and wait, Radiation therapy or a prostatectomy. It sounds like you are doing watch and wait, which is fine.

Latest News?

by Badge414 on Thu Dec 01, 2005 12:00 AM

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What did you find out when you saw your doctor on Nov 23? Your high PSA 0f 8.3 sure looks like a sign of prostate cancer, but the negative biopsies surprise me. As you may know, the current PSA level suggesting the need for further testing is now set at 2.8. High test results can occur if the prostate has an infection, has been massaged or otherwise stimulated by intercourse. All those things will put the antigen in the bloodstream. Your Gleason score is zero, no cancer was detected. As you know, the Gleason score is the sum of the two most prevalent grades of cancer on the scale of one to five, so the maximum Gleason score is 10. Mine was 9, fast growing, aggressive, so I had the radical prostatectomy which missed some of it, so I had 4 months of chemo followed by six months of hormone therapy which I may start again after six months of nothing. My PSA is going back up, so the cancer is still there somewhere, location unknown. You should read info at this site about Magnetic Resonance Spectroscopic Imaging for prostate cancer detection, this is new to me, I had the standard MRI. If you have a small tumor, I would suggest radiation, as surgery and chemo have bad side effects. Jim

High Psa & 3 Negative Biopsies

by Mikeh on Thu Dec 01, 2005 12:00 AM

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Jim, Thanks for the feed back and may your treatment be successful. At my Nov 23 meeting with Dr he gave a prescription for antibiotics. After taking, I will re-test PSA. If infection is causing a hi reading, hopefully, PSA will be down. Mike
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