Photodynamic Therapy For Cancer

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Photodynamic Therapy For Cancer

by Gdpawel on Sat Jan 14, 2006 12:00 AM

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This article focuses on the use of PhotoDynamic Therapy (PDT) for illnesses and diseases. This treatment by light, unlike ultraviolet, infrared and the highly concentrated light of the laser, is said to offer a unique solution for those suffering from cancer as it does not require hospitalization, surgery, chemotherapy, radiation or immunotherapy.

The types of cancer currently being treated by PDT in clinics around the world include Melanoma, Brain, Head, Neck, Oesophagus, Lung, breast, Stomach, Pancreas, Liver, Colon, Ovarian and Prostrate. Pre-cancerous lesions (actinic keratoses) are also said to be treatable using PDT. This therapy can be used to treat not only superficial tumours but large tumours as well and is not contraindicated if other therapies, such as chemo, radiation, etc…are utilized concurrently with it.

According to the author, there is on-going research into the possibility of addressing other types of cancer. Research into other new types of photosensitizing agents is also being carried by Russian pharmaceutical company Radapharma which has developed Radachlorin (Photostem, PhotoFlora), which is a chemically treated form of Spirulina. And in places like the Ukraine, where PDT is well-accepted, herbs like St John's Wort are proving to be of particular research interest.

Closer to home, The Leeds Centre for Photobiology and PDT and the National Medical Laser Centre at the University College of London. PDT is also being studied in non-oncology related illnesses including the treatment of atherosclerosis and both rheumatoid and inflammatory arthritis, among other diseases.

The author concludes that a study for the treatment of Age-Related Macular Degeneration with PDT was performed in 22 centres in Europe and the US resulted in stable or improved vision in 61% of patients treated with PDT with virtually no side-effects.

http://www.positivehealth.com/test/articles.asp?i=1831&b=1

Erbitux and Photodynamic Therapy: Ovarian Cancer

by Gdpawel on Sun Sep 03, 2006 12:00 AM

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Erbitux and Photodynamic Therapy Works Synergistically in Mouse Model of Ovarian Cancer

A new study has found that a treatment regimen that combines the monoclonal antibody C225 (cetuximab, Erbitux) and a method called photodynamic therapy (PDT) is synergistic and well-tolerated in a mouse model of ovarian cancer.

Because the prognosis for women diagnosed with ovarian cancer is poor--less than a third will survive 5 or more years--new treatment strategies are needed. Combination therapies directed against nonoverlapping molecular targets may be the most likely to succeed. Tayyaba Hasan, Ph.D., of Massachusetts General Hospital in Boston, and colleagues tested C225--which inhibits the epidermal growth factor receptor--and PDT--which involves laser-based activation of a light sensitive chemical--separately and in combination in a mouse model of ovarian cancer.

They found that mice treated with both C225 and PDT had a substantial reduction in mean tumor burden to 9.8% of that of no-treatment control mice, whereas mice treated with C225 only or PDT only had mean tumor burdens of 66.6% and 38.2%, respectively. Mice treated with both C225 and PDT also had a nearly three-fold increase in median survival compared with the control mice. When compared with PDT only or C225 only, C225 plus PDT produced synergistic reductions in mean tumor burden and improvements in survival.

In an editorial, Eli Glatstein, M.D., of the University of Pennsylvania in Philadelphia, and colleagues discuss the theoretical advantages of using C225 and PDT to exploit different aspects of ovarian carcinoma tumor biology.

Note: The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute. Attribution to the Journal of the National Cancer Institute is requested in all news coverage. Visit the Journal online at http://jncicancerspectrum.oupjournals.org

Kate Travis jncimedia@oxfordjournals.org Journal of the National Cancer Institute Highlights in the October 19 JNCI http://jncicancerspectrum.oupjournals.org

RE: Photodynamic Therapy For Cancer

by Anitacancer on Fri Dec 15, 2006 12:00 AM

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On 1/14/2006 Gdpawel wrote:

This article focuses on the use of PhotoDynamic Therapy (PDT) for illnesses and diseases. This treatment by light, unlike ultraviolet, infrared and the highly concentrated light of the laser, is said to offer a unique solution for those suffering from cancer as it does not require hospitalization, surgery, chemotherapy, radiation or immunotherapy.

The types of cancer currently being treated by PDT in clinics around the world include Melanoma, Brain, Head, Neck, Oesophagus, Lung, breast, Stomach, Pancreas, Liver, Colon, Ovarian and Prostrate. Pre-cancerous lesions (actinic keratoses) are also said to be treatable using PDT. This therapy can be used to treat not only superficial tumours but large tumours as well and is not contraindicated if other therapies, such as chemo, radiation, etc…are utilized concurrently with it.

According to the author, there is on-going research into the possibility of addressing other types of cancer. Research into other new types of photosensitizing agents is also being carried by Russian pharmaceutical company Radapharma which has developed Radachlorin (Photostem, PhotoFlora), which is a chemically treated form of Spirulina. And in places like the Ukraine, where PDT is well-accepted, herbs like St John's Wort are proving to be of particular research interest.

Closer to home, The Leeds Centre for Photobiology and PDT and the National Medical Laser Centre at the University College of London. PDT is also being studied in non-oncology related illnesses including the treatment of atherosclerosis and both rheumatoid and inflammatory arthritis, among other diseases.

The author concludes that a study for the treatment of Age-Related Macular Degeneration with PDT was performed in 22 centres in Europe and the US resulted in stable or improved vision in 61% of patients treated with PDT with virtually no side-effects.

http://www.positivehealth.com/test/articles.asp?i=1831&b


let this treatment be used before radical disfiguring surgery

 

RE: Photodynamic Therapy For Cancer

by Gdpawel on Sun Nov 04, 2007 12:00 AM

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Revised url address for Photodynamic Therapy For Cancer

http://www.positivehealth.com/article-view.php?articleid=183

 

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