Signet Ring Cell Cancer - 4 year survivor

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RE: Signet Ring Cell Cancer - 4 year survivor

by Fightsignet on Fri Apr 29, 2016 01:15 AM

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What kind of chemo are they going to give your husband. I had 1/3 of my stomach removed at 45 in October 2014. Jan 2015 I had chemo after surgery. FOLFOX 4 cycles. My cancer came back April of this year 2016 to the Retroperitoneal and subclavian lymph nodes. We were told I am not curable. My oncologist wants to give me FOLFIRI.

RE: Signet Ring Cell Cancer - 4 year survivor

by Swessel5597 on Thu Oct 20, 2016 10:15 PM

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My mom was diagnosed with signet ring cell in her colon Dec. 2012. She had surgery in Feb 2013 followed by six months of chemo. Scans were all clear until June 2016, it's back! This time it is in her stomach and we were originally told it was inoperable because of location. She has been on chemo since August. Today we went for a second opinion at Wake Forest in Winston Salem, NC and they have given us a lot of hope. We had a scan today and are hoping it has shrunk enough for surgery to remove it and the HIPEC procedure. We will have more answers at her next appointment when they have gotten the scan results back. My mom feels great and is still very active on her non chemo weeks. Still working and going about life as usual. This is an aggressive cancer but I honestly feel like as long as it is treated aggressively it can be beat!! Please, anyone who reads this keep my mom in your prayers!! She is only 62 and we are not ready to lose her!!

RE: Signet Ring Cell Cancer - 4 year survivor

by WifeFullOfHope on Fri Oct 21, 2016 01:51 PM

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The chemo they tried for my husband were both FOLFOX and FOLFIR plus a million other ones combined (as you probably already know) my husband fell ill again this June an we found out it had spread throughout his stomach/abdomen. He passed on July 30, 2016

xoxothecovered xoxothecovered
(Inactive)

RE: Signet Ring Cell Cancer - 4 year survivor

by xoxothecovered on Fri Oct 21, 2016 02:59 PM

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My father was diagnosed with stage 4 cancer signet ring cell in the stomach on July 15th, 2016. He passed away on the 7th of September, 2016. I would just like to say to everyone whatever you do, do it fast. Signet ring cell is very aggressive.

RE: Signet Ring Cell Cancer - 4 year survivor

by bijubs on Fri Dec 09, 2016 10:36 AM

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On Feb 04, 2015 11:26 PM purplemountaing wrote:

Hi.

I was diagnosed in February 2011 with Stage 3C metestatic cancer in the sigmoid and through the abdominal wall.

I had 17/24 positive lymph nodes.  Had colon resection and FOLFOX.  

I have lived with the terror of this type of cancer and can tell everyone that I was the last person I thought would still be around. 

If anyone needs to communicate with me or wishes to share, please let me know.  Thank you,  Donna

Hello Dona, 

Would like to know whether Dendritic cell therapy can help stage 4 patient who is age 21 with carcinoma stomach her2 negative (score 1) ? 

my daughter is stable in helth as of now, had 6 cycle of cisplatin chemotharaphy (april to july 2016) followed by a surgery on March 13' 2016 both ovarian removed with tumer. 3 days back had a surgery due to intestain block which she was suffering fom last one month. 

Appreciated if any one can suggest about Dendritic cell immuno therapy and its result at this circumstance. 

or what else can do for my daughter? 

regards, Bs ( An Indian )

RE: Signet Ring Cell Cancer - 4 year survivor

by huxuyang on Tue Oct 31, 2017 10:09 PM

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Dear Donna,

I have recurrence of stomach cancer after 3 year of cancer free period. Do you mind let me know what kind of treament you have received? 

Thanks,

Jeffrey

RE: Signet Ring Cell Cancer - 4 year survivor

by purplemountaing on Wed Nov 01, 2017 11:30 AM

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On Oct 31, 2017 10:09 PMhuxuyangwrote:

Dear Donna,

I have recurrence of stomach cancer after 3 year of cancer free period. Do you mind let me know what kind of treament you have received? 

Thanks,

Jeffrey

Hi Jeffrey,

I don't know what type of cancer you had, but I had signet ring cell in my sigmoud colon and I was treated with 12 rounds of FOLFOX cocktail.  I had a high MSI tumor which is believed at this point to be somewhat responsible for my survivorship.

(MSI= microsatellite instability).  I did have a poorly differentiated cancer cell too with a Staging of 3C so it was tough.  

You can reach me directly at if you want to discuss more.

Best and blessings, Donna

RE: Signet Ring Cell Cancer - 4 year survivor

by huxuyang on Wed Nov 01, 2017 11:29 PM

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Donna,

I think I have had Adenocarcinoma and received 4-round of FLOX without any effect. I will receive PD-1 treatment this Friday. 

I am HER-2 negative and cancel cell is middle-level differentiated.

Jeff 

RE: Signet Ring Cell Cancer - 4 year survivor

by lindat585 on Thu Nov 23, 2017 12:28 AM

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I was diagnosed with appendiceal signet ring cell adenocarcinoma in 2012. It was found during a colonoscopy and prior to surgery they thought it was colon cancer.

I was treated with FOLFOX for 12 sessions. That was 5 years ago and I have no cancer.  There is hope.

RE: Signet Ring Cell Cancer - 4 year survivor

by AshokB on Fri Jun 15, 2018 10:51 AM

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On Jul 27, 2015 11:15 PM rohitkrishnan wrote:

Hi MZCutright

We are from India and My Sis is diagnosed with appendicular cancer with high grade signet cell ring last month.She "" target="_blank" rel="nofollow">http://month.She " target="_blank" rel="nofollow">month.She underwent the HIPEC surgery but some deposits are still left behind. she has started the FOLFOX regimen couple of days back..the surgeon ha ssiad that depending on the response to chemo, she may be required to undergo another surgery possibily after an another 8-9 months from now (after her folfox is over ) to remove the rest of the deposits. 

I would say SRCC is definetly tough, but have faith and the picture is not too gloomy. If there is any brightside to SRCC , thenm its that the it usually responds to FOLFOX compared to ther grades of tumours. So hang in there...definetly get a 2nd opinion if the one u r with isin't an expert in dealing with these types of tumors

Hi Rohit, It is very sad that we go thru all this and it really hurts. I live in Dubai and came to Mumbai with my brother and his wife as we had been suggested by doctors at home that she will need a surgery for removal of a vascular mass close to her right ovary. Upon arriving here we went thru tumor marker tests (all in range except for CA125) and then a PET scan which was all clear. Next we planned to have the surgery but taking precautions we had an oncologist surgeon in addition to the gynecologist surgeon on board. At the same time for avoidance of all doubt we had frozen section performed. Unfortunately the result was broken to us that the mass had been found to have signet ring cells that are very aggressive and very poorly defined. As we were dealing with a secondary at this stage the doctors (in addition to her right ovary and fallopian right tube) had her omentum removed. Me and my brother are very nervous as she is only 39 and they have a 12 year old. We can’t gather the courage to tell her and have decided to keep things on hold till we get back the histopath reports from the lab. My questions to the forum are : Does anyone know if it is possible to have signet ring cells originate in the omentum, meaning omentum being the primary source of SRS How long do we have to wait till an endoscopic procedure could possibly performed in order to identify the primary source and gather the biopsy sample If it is gastro SRS what are the options we have Would I be right to assume that she is at advanced stage as we have secondary identified already Rohit, what part of India are you from, could I call and speak to you to get some guidance. We have had all this happen to us in the last 48 hours and we are ind deep shock and sadness. Need all the support and guidance we can get. Thanks, Ashok
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