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Jcancom's Recent CancerCompass Activity

  • Jcancom has replied to a post on the message board

    Something exciting has caught my attention! After reading the latest 3-BP review article I noticed an additional article from China reported with my Google search. My Chinese is not very strong and I was not able to make it through the translation barrier, though I  noticed when I followed this link that there were actually quite a few more Chinese origin 3-BP articles that did not appear with a generic Google s...

    Saturday at 2:11 AM view post
    • Jcancom has replied to a post on the message board

      JohnnyP, it is gratifying that your wife and so many on D's forum are doing reasonably well while under metabolic treatment. As you know, for a few years we did not see patients who consistently maintained benefit even over the short term. Now we have patients who are topping up chemo with anti-metabolic therapy (similar to what appears to be used at the Turkish clinic) and their response to chemo deepens. I would l...

      Saturday at 1:18 AM view post
      • Jcancom has replied to a post on the message board

        Now this is interesting! I have continued to look through a family member's exome file and I spotted some intriguing variants that I had initially overlooked. Surprisingly, I managed to overlook a rare 5utr variant in the MCT-1 gene (i.e., 3-BP's entry portal). The other day I got all hand wavey when I suggested that these variants could be a real game changer for 3-BP. Yet, at the time, I was very unclear how one ...

        March 13 at 1:43 AM view post
        • Jcancom has replied to a post on the message board

          There is a great deal of very exciting research that I have been reading. Near the top of the list are studies that are considering genotype specific responses to treatment. https://www.ncbi.nlm.nih.gov/pubmed/?term=29695106 The thread has taken a moderately strong anti-genetic stance along the lines that cancer is so genetically heterogeneous that specific targetting almost seems hopeless. Reports from the Cancer ...

          March 10 at 10:19 PM view post
          • Jcancom has replied to a post on the message board

            Sorry, JohnnyP, I suspect that there is no universal standard with these DVDs. Each hospital probably just rolls their own and it is a great mystery what button you need to push. According to the rules of good technology, if an interested person can't figure it out, then its not the fault of the person but the fault of the technology. Might try the Readme file. Hopefully it would provide some idea of how to open the...

            March 10 at 9:15 PM view post
            • Jcancom has replied to a post on the message board

              How did we miss this one? Scientific literature indeed! This article is very well written and puts a whole new spin on alkylation. Chemists usually look at 3-BP and immediately dismiss it due to its strong alkylating features. The article notes that chemotherapeutic alkylating agents are at the top of cancer's stigma scale. wiki reports that ethyl bromoacetate was a chemical warfare agent during WW1. Ordinarily, the...

              March 09 at 6:13 PM view post
              • Jcancom has replied to a post on the message board

                critic, thank you for the citation. It is startling how many of these metabolic protocols are being reported. My hard drive is almost jammed pack! It's endless! As I recently mentioned, my suspicion would be that as soon as 3-BP is firmly in the clinic that an entire ecosystem of metabolics will materialize. There are so many treatments that have already been found to synergize with it; I would have to think that the...

                March 08 at 1:42 AM view post
                • Jcancom has replied to a post on the message board

                  3-BP clearly has a great deal of potential and this potential continues to intensify as yet more preclinical research and more formulations are published. In the last month or so I came across another formulation, though it has still not reached pubmed. I am especially excited about using the acetate radiotracer. If this could be used to prescreen responders to 3-BP, then it would greatly reduce the uncertainty that...

                  March 01 at 3:11 AM view post
                  • Jcancom has replied to a post on the message board

                    JohnnyP, thank you for reactivating the thread! As you are no doubt aware, the thread has had many times of near manic excitement, often accompanied with many exclamation marks (!!!!!) {In honestly that has mostly been me}, though usually the follow-on clinical relevance of these eras have been non-existant.  Now, however, for me anyways, the silences, are more profoundly meaningful (as is frequently true). D'...

                    February 27 at 1:27 AM view post
                    • Jcancom has replied to a post on the message board

                      Page 500! Yeah, this is exciting! Moving toward post 5000 with vitality and confidence! The 3-BP story line continues to advance forward and upward! I can hardly wait to see the clinical trial finally start. critic, I came across a very interesting article that talked of how rhodamine ( I believe it was), can clear normal cells within a few hours, though this can take days for cancer cells. It has occurred to me t...

                      February 18 at 1:37 AM view post
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